THE FIRE OF VMS
STARTS IN HER
HYPOTHALAMUS

Altered neuronal activity in her
brain signals the heat1,2

For too long, explanations of Vasomotor Symptoms associated with menopause (VMS), commonly known as hot flashes and night sweats, have been limited to declining estrogen alone. Advances in science have expanded our understanding of the role of specific neuronal pathways in the hypothalamus.1,2

The importance of
NKB in the hot flash cascade

Her VMS need your attention

Making VMS a
priority

References: 1. Rapkin AJ. Vasomotor symptoms in menopause: physiologic condition and central nervous system approaches to treatment. Am J Obstet Gynecol 2007;196(2):97-106. 2. Modi M, Dhillo WS. Neurokinin 3 receptor antagonism: a novel treatment for menopausal hot flushes. Neuroendocrinology
2019;109(3):242-8.